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Breast Cancer Gene Expression: Learn to Walk Before You Can Run

Breast Cancer Gene Expression: Learn to Walk Before You Can Run

  • 12/3/2018 5:00:00 AM
  • View Count 4
Chelsea Goodenough, PhDFrom a young age, we are told “You have to learn to walk, before you can run.” Cell function is no different.Proteins dictate cell function, but what proteins are found in our cells are dictated by the messaging transcriptsthat code for their production. The amounts and types of those coding transcripts, known to scientists asmessenger RNA (mRNA), dictate protein levels and ultimately reflect cellular function. When the transcriptionrate of certain mRNA molecul...
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Rho Kinase, an Important Therapeutic Target in Cardiovascular Health

Rho Kinase, an Important Therapeutic Target in Cardiovascular Health

  • 5/21/2018 6:30:00 AM
  • View Count 514
Song Yi Shin, M.S.Cardiovascular disease (CVD) remains the primary causes of deaths in the United States.Despite a number of research to prevent or cure CVD, it is still the leading cause of morbidity and mortality worldwide. Numerous studies have found that exercise is very effective for prevention of CVD, however, there are many CVD patients who are not able to exercise at high intensity and certain duration required due to their pathological conditions or physical limits. Fortu...
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Vascular Aging And Its Counterpart: We Are All Getting Old

Vascular Aging And Its Counterpart: We Are All Getting Old

  • 4/23/2018 5:30:00 AM
  • View Count 574
Song Yi Shin, M.S.How can you improve your vascular health? You would undoubtedly answer that it is the exercise, and it is true. Your arteries deliver blood and oxygen to organs and skeletal muscle. When you start to exercise, your legs would need more blood to match the metabolic demands. At rest, a majority of your blood volume is in your veins. But during exercise, blood flow through tissues change dramatically, with 85% of blood going to your active muscles through arteries in hea...
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Can Exercise Protect Your Memory?

Can Exercise Protect Your Memory?

  • 4/16/2018 5:30:00 AM
  • View Count 541
Jing Chen, Ph.D.Aerobic exercise can help motor skill learning by protecting previously learned procedural memory from subsequent interference tasks (for example, subsequent declarative memory). The primary motor cortex may play an important role during this process. When we examine this has happened, we will perform three experiments to see if our hypothesis is true. In the first two experiments, we let participants perform procedural memory immediately followed by declarative memory or a ...
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What Horses Can Tell Us About Humans

What Horses Can Tell Us About Humans

  • 3/26/2018 6:30:00 AM
  • View Count 641
Christine Latham, M.S.Currently, rodents are the most commonly used model for human aging, but because they have much shorter lifespans and many physical dissimilarities from humans, they may not be the best possible model for humans. So, what should we use if the time-honored rodent model is not the best option? Interestingly enough, horses may be able to fill the gap between easy-to-use mouse models and hard-to-control human studies. But why horses? Horses are an athletic species, they have th...
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Are MicroRNA's the Connection Between Exercise and Breast Cancer?

Are MicroRNA's the Connection Between Exercise and Breast Cancer?

  • 3/5/2018 6:30:00 AM
  • View Count 588
Chelsea Goodenough, HBScBreast cancer is the most common type of cancer that kills women world-wide [1]. Emerging out from under the emotional and financial burden of this disease is the united front of patients, families and researchers alike seeking to understand the complexity of this disease. With exercise's noted benefit to a 30-40% reduction in breast cancer risk, investigation into mechanisms that may be attributing to these findings have unveiled a frontrunner - microRNA. MicroRNA ar...
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Nutrition and Exercise: Timing is Everthing

Nutrition and Exercise: Timing is Everthing

  • 2/19/2018 6:30:00 AM
  • View Count 811
Tyler Grubic, M.S.Intense weight lifting and/or sprints, including acute single bouts, can promote exercise-induced stress responses, characterized by muscle damage and inflammation similar to stress associated with cardiovascular events and illnesses [10-12]. Decreased performance due to muscle soreness is not the direct result of inflammation, but rather a product of pain and mechanical receptor sensitivity to products of muscle breakdown, such as circulating chemicals and intramuscular protei...
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Think BIG, Start SMALL: MicroRNAs and Breast Cancer

Think BIG, Start SMALL: MicroRNAs and Breast Cancer

  • 12/4/2016 5:22:00 PM
  • View Count 3382
Chelsea Goodenough, B.S.The human body is capable of powerful things. When in prime condition, we are capable of adrenaline induced She-Hulk strength, and fighting the effect of zero gravity by walking on the moon. This, to most of us, is recognizable as disease, and is amongst us in the form of diabetes, heart disease, obesity, and chronic obstructive pulmonary disease (COPD) to name only a few. A disease that affects nearly 246,660 new people every year, is breast cancer, with an estimated 40,...
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Exercise Can Provide Protection In Extreme Situations

Exercise Can Provide Protection In Extreme Situations

  • 11/27/2016 6:09:00 PM
  • View Count 1193
Rihana Bokhari, B.S.You have probably heard before that exercise is good for you. You know that doctors recommend people in disease states exercise, for instance in diabetes and heart disease. But did you know that exercise can do far more than help you look good and feel great? Exercise may be able to protect you if you are exposed to radiation. Radiation is well known to have negative effects on the body and lead to illness and loss of life. In this study we seek to understand how exercise, an...
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Does Time Decrease Enthusiasm For Play?

Does Time Decrease Enthusiasm For Play?

  • 10/28/2016 2:04:00 AM
  • View Count 1043
Jiling Liu, M. Ed Regular physical activity (PA) is important for children’s health and development. Exercising daily can reduce heart disease, obesity, and bone problems. Regular PA burns out stress and makes people feel good. Children’s academic learning can also improve through habitual exercises. Recently, PA opportunities for children are becoming fewer. One reason is that schools have focused more on students’ academic performances. At the same time, schools have cu...
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